All terms in COVID

Label Id Description
attachment of spindle microtubules to kinetochore GO_0008608 [The process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex.]
AGTR1 OGG_3000000185
protein activation cascade GO_0072376 [A response to a stimulus that consists of a sequential series of modifications to a set of proteins where the product of one reaction acts catalytically in the following reaction. The magnitude of the response is typically amplified at each successive step in the cascade. Modifications typically include proteolysis or covalent modification, and may also include binding events.]
MACROD1 OGG_3000028992
tigecycline CHEBI_149836 [Tetracycline in which the hydroxy group at position 5 and the methyl group at position 6 are replaced by hydrogen, and with a dimethylamino substituent and an (N-tert-butylglycyl)amino substituent at positions 7 and 9, respectively. A glycylcycline antibiotic, it has activity against a broad range of Gram-positive and Gram-negative bacteria, including tetracycline-resistant organisms. It is used for the intravenous treatment of complicated skin and skin structure infections caused by susceptible organisms.]
antimicrobial humoral response GO_0019730 [An immune response against microbes mediated through a body fluid. Examples of this process are seen in the antimicrobial humoral response of Drosophila melanogaster and Mus musculus.]
small nuclear ribonucleoprotein complex GO_0030532 [A complex composed of RNA of the small nuclear RNA (snRNA) class and protein, found in the nucleus of a eukaryotic cell. These are typically named after the snRNA(s) they contain, e.g. U1 snRNP or U4/U6 snRNP. Many, but not all, of these complexes are involved in splicing of nuclear mRNAs.]
pentamidine CHEBI_45081 [A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.]
lethargy SYMP_0000075 [Lethargy is a fatigue characterized as abnormal drowsiness.]
negative regulation of metaphase/anaphase transition of cell cycle GO_1902100 [Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of cell cycle.]
Abnormality of the endocrine system HP_0000818 [An abnormality of the endocrine system.]
Sapanisertib NCIT_C90548 [An orally bioavailable inhibitor of raptor-mTOR (TOR complex 1 or TORC1) and rictor-mTOR (TOR complex 2 or TORC2) with potential antineoplastic activity. Sapanisertib binds to and inhibits both TORC1 and TORC2 complexes of mTOR, which may result in tumor cell apoptosis and a decrease in tumor cell proliferation. TORC1 and 2 are upregulated in some tumors and play an important role in the PI3K/Akt/mTOR signaling pathway, which is frequently dysregulated in human cancers.]
T follicular helper cell CL_0002038 [A CD4-positive, CXCR5-positive, CCR7-negative alpha-beta T cell located in follicles of secondary lymph nodes that expresses is BCL6-high, ICOS-high and PD1-high, and stimulates follicular B cells to undergo class-switching and antibody production.]
signaling receptor binding GO_0005102 [Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.]
daunorubicin CHEBI_41977 [A natural product found in Actinomadura roseola.]
Abnormal renal physiology HP_0012211 [An abnormal functionality of the kidney.]
Abnormal blood ion concentration HP_0003111 [Abnormality of the homeostasis (concentration) of a monoatomic ion.]
Thioredoxin-1 Inhibitor PX-12 NCIT_C74082 [An orally bioavailable small molecule with potential antineoplastic activity. Thioredoxin-1 inhibitor PX-12 irreversibly binds to thioredoxin-1 (Trx-1) and inhibits its activity, which may result in growth inhibition and the induction of apoptosis. Overexpressed in many cancer cell types, the low molecular weight redox protein Trx-1 regulates transcription factor activity and inhibits apoptosis, promoting cell growth and survival; it also interacts with growth factors extracellularly to stimulate cell growth.]
CD3G OGG_3000000917
disulfiram CHEBI_4659 [An organic disulfide that results from the formal oxidative dimerisation of N,N-diethyldithiocarbamic acid. A multi-enzyme inhibitor that is used in alcohol aversion therapy and also exhibits anticancer properties.]