|
GRB2 Adaptor Protein
|
D051380 |
[A signal transducing adaptor protein that links extracellular signals to the MAP KINASE SIGNALING SYSTEM. Grb2 associates with activated EPIDERMAL GROWTH FACTOR RECEPTOR and PLATELET-DERIVED GROWTH FACTOR RECEPTORS via its SH2 DOMAIN. It also binds to and translocates the SON OF SEVENLESS PROTEINS through its SH3 DOMAINS to activate PROTO-ONCOGENE PROTEIN P21(RAS).
] |
|
Rats
|
D051381 |
[The common name for the genus Rattus.
] |
|
GRB7 Adaptor Protein
|
D051382 |
[A SH2 DOMAIN-containing protein that mediates SIGNAL TRANSDUCTION pathways from multiple CELL SURFACE RECEPTORS, including the EPHB1 RECEPTOR. It interacts with FOCAL ADHESION KINASE and is involved in CELL MIGRATION.
] |
|
2-2'-dimethoxy-3,3'-dihydro-5,5'-oxygen-6,6'-biphenylformic anhydride
|
C115230 |
|
|
GRB10 Adaptor Protein
|
D051383 |
[A binding partner for several RECEPTOR PROTEIN-TYROSINE KINASES, including INSULIN RECEPTOR and INSULIN-LIKE GROWTH FACTOR RECEPTOR. It contains a C-terminal SH2 DOMAIN and mediates various SIGNAL TRANSDUCTION pathways.
] |
|
6-methoxy butyl phthalide
|
C115231 |
|
|
benzyl caffeate
|
C115232 |
|
|
Cortactin
|
D051356 |
[A microfilament protein that interacts with F-ACTIN and regulates cortical actin assembly and organization. It is also an SH3 DOMAIN containing phosphoprotein, and it mediates tyrosine PHOSPHORYLATION based SIGNAL TRANSDUCTION by PROTO-ONCOGENE PROTEIN PP60(C-SRC).
] |
|
Cyclin-Dependent Kinase 2
|
D051357 |
[A key regulator of CELL CYCLE progression. It partners with CYCLIN E to regulate entry into S PHASE and also interacts with CYCLIN A to phosphorylate RETINOBLASTOMA PROTEIN. Its activity is inhibited by CYCLIN-DEPENDENT KINASE INHIBITOR P27 and CYCLIN-DEPENDENT KINASE INHIBITOR P21.
] |
|
Cyclin-Dependent Kinase 4
|
D051358 |
[Cyclin-dependent kinase 4 is a key regulator of G1 PHASE of the CELL CYCLE. It partners with CYCLIN D to phosphorylate RETINOBLASTOMA PROTEIN. CDK4 activity is inhibited by CYCLIN-DEPENDENT KINASE INHIBITOR P16.
] |
|
Lymphohistiocytosis, Hemophagocytic
|
D051359 |
[A group of related disorders characterized by LYMPHOCYTOSIS; HISTIOCYTOSIS; and hemophagocytosis. The two major forms are familial and reactive.
] |
|
5-acetoxyacetylimino-4-methyl-delta(2)-1,3,4-thiadiazoline-2-sulfonamide
|
C115288 |
|
|
wlaB protein, Campylobacter jejuni
|
C115291 |
|
|
Thumb deformity, alopecia, pigmentation anomaly
|
C536904 |
|
|
wlaG protein, Campylobacter jejuni
|
C115292 |
|
|
Thymic epithelial tumor
|
C536905 |
|
|
1-(carboxymethyl)-3,5-diphenyl-2-methylbenzene
|
C115293 |
|
|
beta-naphthylsulfonyl-R-(d-Pip)-Ada-Abu-DYEPIPEEA-(Cha)-(d-Glu)-OH-AcOH
|
C115294 |
|
|
Thymic-Renal-Anal-Lung dysplasia
|
C536907 |
|
|
beta-naphthylsulfonyl-(d-Pip)-Ada-Abu-DFEEIPEEYLQ-OH-AcOH
|
C115295 |
|
