|
Early Growth Response Transcription Factors
|
D051765 |
[A family of transcription factors that are induced by GROWTH FACTORS and contain a highly conserved DNA-binding domain composed of three ZINC FINGER MOTIFS.
] |
|
Mononuclear Phagocyte System
|
D012157 |
[Mononuclear cells with pronounced phagocytic ability that are distributed extensively in lymphoid and other organs. It includes MACROPHAGES and their precursors; PHAGOCYTES; KUPFFER CELLS; HISTIOCYTES; DENDRITIC CELLS; LANGERHANS CELLS; and MICROGLIA. The term mononuclear phagocyte system has replaced the former reticuloendothelial system, which also included less active phagocytic cells such as fibroblasts and endothelial cells. (From Illustrated Dictionary of Immunology, 2d ed.)
] |
|
Osmium-189
|
C000615084 |
|
|
Early Growth Response Protein 1
|
D051766 |
[An early growth response transcription factor and zinc finger protein that has been implicated in regulation of CELL PROLIFERATION and APOPTOSIS.
] |
|
Proto-Oncogene Proteins c-mdm2
|
D051736 |
[An E3 UBIQUITIN LIGASE that interacts with and inhibits TUMOR SUPPRESSOR PROTEIN P53. Its ability to ubiquitinate p53 is regulated by TUMOR SUPPRESSOR PROTEIN P14ARF.
] |
|
Origin Recognition Complex
|
D051738 |
[The origin recognition complex is a multi-subunit DNA-binding protein that initiates DNA REPLICATION in eukaryotes.
] |
|
Retinal Vein Occlusion
|
D012170 |
[Blockage of the RETINAL VEIN. Those at high risk for this condition include patients with HYPERTENSION; DIABETES MELLITUS; ATHEROSCLEROSIS; and other CARDIOVASCULAR DISEASES.
] |
|
Microphthalmia-Associated Transcription Factor
|
D051739 |
[A basic helix-loop-helix leucine zipper transcription factor that regulates the CELL DIFFERENTIATION and development of a variety of cell types including MELANOCYTES; OSTEOCLASTS; and RETINAL PIGMENT EPITHELIUM. Mutations in MITF protein have been associated with OSTEOPETROSIS and WAARDENBURG SYNDROME.
] |
|
Retinal Vessels
|
D012171 |
[The blood vessels which supply and drain the RETINA.
] |
|
Retinaldehyde
|
D012172 |
[A carotenoid constituent of visual pigments. It is the oxidized form of retinol which functions as the active component of the visual cycle. It is bound to the protein opsin forming the complex rhodopsin. When stimulated by visible light, the retinal component of the rhodopsin complex undergoes isomerization at the 11-position of the double bond to the cis-form; this is reversed in "dark" reactions to return to the native trans-configuration.
] |
|
Trim7 protein, mouse
|
C482978 |
|
|
CR1L protein, human
|
C482970 |
|
|
Retinal Degeneration
|
D012162 |
[A retrogressive pathological change in the retina, focal or generalized, caused by genetic defects, inflammation, trauma, vascular disease, or aging. Degeneration affecting predominantly the macula lutea of the retina is MACULAR DEGENERATION. (Newell, Ophthalmology: Principles and Concepts, 7th ed, p304)
] |
|
MARK4 protein, mouse
|
C482979 |
|
|
Retinal Detachment
|
D012163 |
[Separation of the inner layers of the retina (neural retina) from the pigment epithelium. Retinal detachment occurs more commonly in men than in women, in eyes with degenerative myopia, in aging and in aphakia. It may occur after an uncomplicated cataract extraction, but it is seen more often if vitreous humor has been lost during surgery. (Dorland, 27th ed; Newell, Ophthalmology: Principles and Concepts, 7th ed, p310-12).
] |
|
Retinal Diseases
|
D012164 |
[Diseases involving the RETINA.
] |
|
Retinal Ganglion Cells
|
D012165 |
[Neurons of the innermost layer of the retina, the internal plexiform layer. They are of variable sizes and shapes, and their axons project via the OPTIC NERVE to the brain. A small subset of these cells act as photoreceptors with projections to the SUPRACHIASMATIC NUCLEUS, the center for regulating CIRCADIAN RHYTHM.
] |
|
Retinal Hemorrhage
|
D012166 |
[Bleeding from the vessels of the retina.
] |
|
Retinal Perforations
|
D012167 |
[Perforations through the whole thickness of the retina including the macula as the result of inflammation, trauma, degeneration, etc. The concept includes retinal breaks, tears, dialyses, and holes.
] |
|
Retinal Pigments
|
D012168 |
[Photosensitive protein complexes of varied light absorption properties which are expressed in the PHOTORECEPTOR CELLS. They are OPSINS conjugated with VITAMIN A-based chromophores. Chromophores capture photons of light, leading to the activation of opsins and a biochemical cascade that ultimately excites the photoreceptor cells.
] |
