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protein farnesyltransferase activity
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GO_0004660 |
[Catalysis of the reaction: farnesyl diphosphate + protein-cysteine = S-farnesyl protein + diphosphate.] |
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protein prenyltransferase activity
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GO_0008318 |
[Catalysis of the covalent addition of an isoprenoid group such as a farnesyl or geranylgeranyl group via thioether linkages to a cysteine residue in a protein.] |
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protein geranylgeranyltransferase activity
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GO_0004661 |
[Catalysis of the covalent addition of a geranylgeranyl (20-carbon isoprenoid) group via thioether linkages to a cysteine residue at or near the C terminus of a protein.] |
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CAAX-protein geranylgeranyltransferase activity
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GO_0004662 |
[Catalysis of the reaction: geranylgeranyl diphosphate + protein-cysteine = S-geranylgeranyl-protein + diphosphate. This reaction is the formation of a thioether linkage between the C-1 atom of the geranylgeranyl group and a cysteine residue fourth from the C-terminus of the protein. The protein substrates have the C-terminal sequence CA1A2X, where the terminal residue, X, is preferably leucine and A2 should not be aromatic. Known substrates include most g-subunits of heterotrimeric G proteins and Ras-related GTPases such as members of the Ras and Rac/Rho families.] |
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Rab geranylgeranyltransferase activity
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GO_0004663 |
[Catalysis of the reaction: 2 geranylgeranyl diphosphate + protein-cysteine = 2 S-geranylgeranyl-protein + 2 diphosphate. This reaction is the formation of two thioether linkages between the C-1 atom of the geranylgeranyl groups and two cysteine residues within the terminal sequence motifs XXCC, XCXC or CCXX. Known substrates include Ras-related GTPases of a single family and the Rab family.] |
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prephenate dehydratase activity
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GO_0004664 |
[Catalysis of the reaction: prephenate = phenylpyruvate + H2O + CO2.] |
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prephenate dehydrogenase (NADP+) activity
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GO_0004665 |
[Catalysis of the reaction: NADP+ + prephenate = (4-hydroxyphenyl)pyruvate + CO2 + NADPH.] |
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prostaglandin-endoperoxide synthase activity
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GO_0004666 |
[Catalysis of the reaction: (5Z,8Z,11Z,14Z)-eicosatetraenoate + AH2 + 2 O2 = A + H2O + prostaglandin H2.] |
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prostaglandin-D synthase activity
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GO_0004667 |
[Catalysis of the reaction: prostaglandin H(2) = prostaglandin D(2).] |
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protein-arginine deiminase activity
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GO_0004668 |
[Catalysis of the reaction: H2O + L-arginyl-[protein] = L-citrullyl-[protein] + NH4+, resulting in citrullination of the target protein. This reaction is calcium-dependent.] |
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protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
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GO_0004671 |
[Catalysis of the reaction: S-adenosyl-L-methionine + protein C-terminal S-farnesyl-L-cysteine = S-adenosyl-L-homocysteine + protein C-terminal S-farnesyl-L-cysteine methyl ester.] |
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protein C-terminal carboxyl O-methyltransferase activity
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GO_0003880 |
[Catalysis of the transfer of a methyl group to the oxygen atom of a carboxyl group at the C-terminal of a protein.] |
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phosphotransferase activity, nitrogenous group as acceptor
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GO_0016775 |
[Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a nitrogenous group (acceptor).] |
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3-phosphoinositide-dependent protein kinase activity
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GO_0004676 |
[Phosphatidylinositol-3-phosphate-dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein.] |
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DNA-dependent protein kinase activity
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GO_0004677 |
[DNA dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein.] |
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GO_0004678
|
GO_0004678 |
|
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AMP-activated protein kinase activity
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GO_0004679 |
[Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of AMP.] |
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positive regulation of microglia differentiation
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GO_0014008 |
[Any process that activates, maintains or increases the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell.] |
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positive regulation of macrophage differentiation
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GO_0045651 |
[Any process that activates or increases the frequency, rate or extent of macrophage differentiation.] |
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regulation of microglia differentiation
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GO_0014006 |
[Any process that modulates the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell.] |