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thymidylate synthase activity
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GO_0004799 |
[Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP = 7,8-dihydrofolate + thymidylate.] |
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5,10-methylenetetrahydrofolate-dependent methyltransferase activity
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GO_0042083 |
[Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5,10-methylenetetrahydrofolate.] |
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C-C chemokine receptor CCR7 signaling pathway
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GO_0038118 |
[The series of molecular signals initiated by a the C-C chemokine type 7 receptor on the surface of a cell binding to one of it's physiological ligands, and ending with the regulation of a downstream cellular process, e.g. transcription.] |
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CCL19-activated CCR7 signaling pathway
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GO_0038119 |
[The series of molecular signals initiated by the binding of the C-C chemokine CCL19 to a C-C chemokine type 7 receptor (CCR7) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.] |
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chemokine (C-C motif) ligand 19 signaling pathway
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GO_0038115 |
[The series of molecular signals initiated by the binding of the C-C chemokine CCL19 to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.] |
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interleukin-21-mediated signaling pathway
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GO_0038114 |
[The series of molecular signals initiated by interleukin-21 binding to a receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.] |
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chemokine (C-C motif) ligand 21 signaling pathway
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GO_0038116 |
[The series of molecular signals initiated by the binding of the C-C chemokine CCL21 to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.] |
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C-C motif chemokine 19 receptor activity
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GO_0038117 |
[Combining with the C-C motif chemokine 19 (CCL19) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.] |
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interleukin-2-mediated signaling pathway
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GO_0038110 |
[The series of molecular signals initiated by interleukin-2 binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.] |
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interleukin-7-mediated signaling pathway
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GO_0038111 |
[The series of molecular signals initiated by interleukin-7 binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.] |
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interleukin-8-mediated signaling pathway
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GO_0038112 |
[The series of molecular signals initiated by interleukin-8 binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.] |
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interleukin-9-mediated signaling pathway
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GO_0038113 |
[The series of molecular signals initiated by interleukin-9 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.] |
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obsolete nodal signaling pathway involved in determination of left/right asymmetry
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GO_0038107 |
[OBSOLETE. The series of molecular signals initiated by a nodal protein binding of to an activin receptor on the surface of a target cell, which contributes to the establishment of an organism's body plan or part of an organism with respect to the left and right halves.] |
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negative regulation of appetite by leptin-mediated signaling pathway
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GO_0038108 |
[The series of molecular signals initiated by leptin binding to its receptor on the surface of a cell, which reduces appetite, the desire or physical craving for food.] |
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negative regulation of appetite
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GO_0032099 |
[Any process that reduces appetite.] |
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leptin-mediated signaling pathway
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GO_0033210 |
[The series of molecular signals initiated by leptin binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body.] |
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Kit signaling pathway
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GO_0038109 |
[The series of molecular signals initiated by the binding of stem cell factor to the tyrosine kinase receptor KIT on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Stem cell factor (KIT ligand) binding to the receptor Kit mediates receptor dimerization, activation of its intrinsic tyrosine kinase activity and autophosphorylation. The activated receptor then phosphorylates various substrates, thereby activating distinct signaling cascades within the cell that trigger a change in state or activity of the cell.] |
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obsolete activin receptor antagonist activity involved in negative regulation of nodal signaling pathway
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GO_0038103 |
[OBSOLETE. Interacting with an activin receptor to reduce the action of the agonist nodal. A receptor antagonist does not initiate signaling upon binding to a receptor, but instead blocks an agonist from binding to the receptor.] |
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nodal receptor complex
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GO_0038104 |
[A protein complex containing at least a type II activin receptor, a type I activin receptor, and a coreceptor (EGF-CFC protein) such as Cripto or Cryptic. Nodal receptor complexes are capable of binding a nodal protein and transducing the signal into the cell.] |
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sequestering of TGFbeta from receptor via TGFbeta binding
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GO_0038105 |
[Binding to a transforming growth factor-beta (TGFbeta) protein in the extracellular region, and inhibiting TGFbeta signaling by preventing TGFbeta from binding to its cell surface receptor.] |