All terms in GO

Label Id Description
protein-RNA complex disassembly GO_0032988 [The disaggregation of a protein-RNA complex into its constituent components.]
spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) GO_0000388 [Rearrangement of the pre-catalytic spliceosome containing U4 (or U4atac) and U1 (or U11) snRNPs to unpair U4 (or U4atac) from U6 (or U6atac) and release it from the spliceosomal complex along with U1 (or U11).]
second spliceosomal transesterification activity GO_0000386 [Catalysis of the second transesterification reaction of spliceosomal mRNA splicing. Ligation of the two exons occurs via a transesterification reaction where the free 3'-hydroxyl group of the 5' exon is the nucleophile attacking the 3' splice site. Non-expressed sequences are now detached from the exons. In cis splicing, the intron is in a lariat structure.]
spliceosomal snRNP assembly GO_0000387 [The aggregation, arrangement and bonding together of one or more snRNA and multiple protein components to form a ribonucleoprotein complex that is involved in formation of the spliceosome.]
first spliceosomal transesterification activity GO_0000384 [Catalysis of the first transesterification reaction of spliceosomal mRNA splicing. The intron branch site adenosine is the nucleophile attacking the 5' splice site, resulting in cleavage at this position. In cis splicing, this is the step that forms a lariat structure of the intron RNA, while it is still joined to the 3' exon.]
GO_0000385 GO_0000385
GO_0000382 GO_0000382
GO_0000383 GO_0000383
alternative mRNA splicing, via spliceosome GO_0000380 [The process of generating multiple mRNA molecules from a given set of exons by differential use of exons from the primary transcript(s) to form multiple mature mRNAs that vary in their exon composition.]
regulation of alternative mRNA splicing, via spliceosome GO_0000381 [Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs.]
regulation of mRNA splicing, via spliceosome GO_0048024 [Any process that modulates the frequency, rate or extent of mRNA splicing via a spliceosomal mechanism.]
tRNA-type intron splice site recognition and cleavage GO_0000379 [RNA processing that begins when the tertiary structure of a tRNA type intron is recognized, and ends when the endonucleolytic cleavage of the RNA at both the 5' and 3' splice sites occurs.]
RNA splicing, via transesterification reactions GO_0000375 [Splicing of RNA via a series of two transesterification reactions.]
RNA splicing, via transesterification reactions with guanosine as nucleophile GO_0000376 [Splicing of RNA via a series of two transesterification reactions with exogenous guanosine as the initiating nucleophile.]
Group II intron splicing GO_0000373 [The splicing of Group II introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group II introns and containing splice site consensus sequences, that is involved in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions (mechanistically similar to those for splicing of nuclear mRNAs) initiated by a bulged adenosine residue within the intron sequence as the initiating nucleophile. The intron is excised as a lariat.]
Group III intron splicing GO_0000374 [The splicing of Group III introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group III introns, that is involved in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions begun by a bulged adenosine residue within the intron sequence as the initiating nucleophile. The intron is excised as a lariat. Though very similar in structure and mechanism to Group II introns, Group III introns are smaller and more streamlined and the splice site consensus sequences are not as well conserved.]
GO_0000371 GO_0000371
Group I intron splicing GO_0000372 [The splicing of Group I introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group I introns and involved in determining the locations of the splice sites (there do not appear to be consensus splice site sequences) as well as having a role in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions, generally with exogenous guanosine as the initiating nucleophile. The intron is excised as a linear piece (though it may subsequently circularize).]
GO_0000370 GO_0000370
GO_0000368 GO_0000368