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cerebral cortex neuron differentiation
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GO_0021895 |
[The process in which a relatively unspecialized cell acquires specialized features of a neuron residing in the cerebral cortex.] |
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hypoxia-inducible factor-1alpha signaling pathway
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GO_0097411 |
[The series of molecular signals mediated by hypoxia-inducible factor (HIF1) in response to lowered oxygen levels (hypoxia). Under hypoxic conditions, the oxygen-sensitive alpha-subunit of hypoxia-inducible factor (HIF)-1 dimerizes with a HIF1-beta subunit (also called ARNT or aryl-hydrocarbon-receptor nuclear translocator), translocates to the nucleus and activates transcription of genes whose products participate in responding to hypoxia.] |
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hyaline inclusion
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GO_0097412 |
[A glass-like, pale intracellular inclusion.] |
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obsolete replication fork protection
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GO_0048478 |
[OBSOLETE. Any process that prevents the collapse of stalled replication forks.] |
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Lewy body
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GO_0097413 |
[Cytoplasmic, spherical inclusion commonly found in damaged neurons, and composed of abnormally phosphorylated, neurofilament proteins aggregated with ubiquitin and alpha-synuclein.] |
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style development
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GO_0048479 |
[The process whose specific outcome is the progression of the style over time, from its formation to the mature structure. The style is an elongated part of a carpel, or group of fused carpels, and it lies between the ovary and the stigma.] |
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classical Lewy body
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GO_0097414 |
[Cytoplasmic inclusion, 5 to 15 micrometers in diameter, with a dense core surrounded by a halo of 10 to 20 nm wide radially oriented alpha-synuclein fibrils.] |
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Holliday junction resolvase complex
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GO_0048476 |
[An endodeoxyribonuclease complex that resolves the 4-way DNA intermediates of a Holliday junction into two separate duplex DNA molecules. Can be branch-migration associated.] |
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cortical Lewy body
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GO_0097415 |
[Cytoplasmic inclusion similar to a classical Lewy body but lacking a halo of protein fibrils.] |
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oogenesis
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GO_0048477 |
[The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster.] |
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female gamete generation
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GO_0007292 |
[Generation of the female gamete; specialised haploid cells produced by meiosis and along with a male gamete takes part in sexual reproduction.] |
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Lewy body-like hyaline inclusion
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GO_0097416 |
[Cytoplasmic inclusion found in neurons. It consists of filaments and granular materials, exhibits a dense core with a rough peripheral halo and lacks a limiting membrane. The filaments of these inclusions are composed of approximately 15-25 nm granule-coated fibrils in association with normal 10-nm neurofilaments.] |
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nematosome
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GO_0097417 |
[Cytoplasmic, ball-like inclusion resembling a nucleolus and consisting of a convoluted network of electron-opaque strands embedded in a less dense matrix. It measures approximately 0.9 microns and lacks a limiting membrane. Its strands (diameter = 400-600 A) appear to be made of an entanglement of tightly packed filaments and particles approximately 25-50 A thick. Cytochemical studies suggest the presence of nonhistone proteins and some RNA. Usually only one such structure is present in a cell, and it appears to occur in most ganglion cells. Although they can be seen anywhere in the cell body, nematosomes are typically located in the perinuclear cytoplasm, where they are often associated with smooth-surfaced and coated vesicles.] |
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neurofibrillary tangle
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GO_0097418 |
[Intracellular mass of paired, helically wound protein filaments (also called PHF) lying in the cytoplasm of neuronal cell bodies and neuritic cell processes. Neurofibrillary tangles contain an abnormally phosphorylated form of a microtubule-associated protein, tau. The shape of these inclusions may resemble a flame or a star.] |
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Pick body
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GO_0097419 |
[Cellular inclusion composed of numerous tau fibrils arranged in a disorderly array. Tau protein is a major component, though Pick bodies also contain ubiquitin, alpha-synuclein, and apolipoprotein E.] |
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GO_0048470
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GO_0048470 |
|
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GO_0048474
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GO_0048474 |
|
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coated membrane
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GO_0048475 |
[A single or double lipid bilayer with any of several different proteinaceous coats that can associate with membranes. Membrane coats include those formed by clathrin plus an adaptor complex, the COPI and COPII complexes.] |
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threonine-phosphate decarboxylase activity
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GO_0048472 |
[Catalysis of the reaction: O-phospho-L-threonine + H+ = (R)-1-aminopropan-2-yl phosphate + CO2.] |
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D-methionine transmembrane transport
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GO_0048473 |
[The process in which D-methionine is transported across a lipid bilayer, from one side of a membrane to the other.] |