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ubiquitin-specific protease binding
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GO_1990381 |
[Binding to a ubiquitin-specific protease.] |
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protease binding
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GO_0002020 |
[Binding to a protease or a peptidase.] |
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obsolete melanosome assembly
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GO_1990382 |
[OBSOLETE. The aggregation, arrangement and bonding together of a set of components to form a melanosome, a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored.] |
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K48-linked deubiquitinase activity
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GO_1990380 |
[Hydrolysis of a ubiquitin unit from a ubiquitinated protein linked via the Lys48 residue of ubiquitin.] |
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deubiquitinase activity
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GO_0101005 |
[An isopeptidase activity that cleaves ubiquitin from a target protein to which it is conjugated.] |
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discoidal high-density lipoprotein particle
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GO_0034365 |
[A newly formed high-density lipoprotein particle; consists of a phospholipid bilayer surrounded by two or more APOA1 molecules. The discoidal HDL particle is formed when lipid-free or lipid-poor APOA1 acquires phospholipids and unesterified cholesterol from either cell membranes or triglyceride-rich lipoproteins (undergoing lipolysis by lipoprotein lipase).] |
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high-density lipoprotein particle
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GO_0034364 |
[A lipoprotein particle with a high density (typically 1.063-1.21 g/ml) and a diameter of 5-10 nm that contains APOAs and may contain APOCs and APOE; found in blood and carries lipids from body tissues to the liver as part of the reverse cholesterol transport process.] |
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spherical high-density lipoprotein particle
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GO_0034366 |
[A mature high-density lipoprotein (HDL) particle, converted from discoidal HDL particles following the esterification of cholesterol in the particle by phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT).] |
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intermediate-density lipoprotein particle
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GO_0034363 |
[A triglyceride-rich lipoprotein particle that typically contains APOB100, APOE and APOCs and has a density of 1.006-1.019 g/ml and a diameter of between 25-30 nm. IDL particles are found in blood and are formed by the delipidation of very-low-density lipoprotein particles (VLDL). IDL particles are removed from blood by the liver, following binding to the APOE receptor, or are converted to low-density lipoprotein (LDL).] |
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triglyceride-rich plasma lipoprotein particle
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GO_0034385 |
[A plasma lipoprotein particle that has a hydrophobic core enriched in triglycerides surrounded by an amphipathic monolayer of phospholipids, cholesterol and apolipoproteins. Triglyceride-rich lipoprotein particles transport lipids, which are non-covalently associated with the particles, in the blood.] |
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protein-lipid complex remodeling
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GO_0034368 |
[The acquisition, loss or modification of a protein or lipid within a protein-lipid complex.] |
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protein-containing complex remodeling
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GO_0034367 |
[The acquisition, loss, or modification of macromolecules within a complex, resulting in the alteration of an existing complex.] |
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protein-containing complex organization
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GO_0043933 |
[Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein complex.] |
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protein-lipid complex organization
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GO_0071825 |
[Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-lipid complex.] |
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very-low-density lipoprotein particle
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GO_0034361 |
[A triglyceride-rich lipoprotein particle that is typically composed of APOB100, APOE and APOCs and has a density of about 1.006 g/ml and a diameter of between 20-80 nm. It is found in blood and transports endogenous products (newly synthesized cholesterol and triglycerides) from the liver.] |
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low-density lipoprotein particle
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GO_0034362 |
[A lipoprotein particle, rich in cholesterol esters and low in triglycerides that is typically composed of APOB100 and APOE and has a density of 1.02-1.06 g/ml and a diameter of between 20-25 nm. LDL particles are formed from VLDL particles (via IDL) by the loss of triglyceride and gain of cholesterol ester. They transport endogenous cholesterol (and to some extent triglycerides) from peripheral tissues back to the liver.] |
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chylomicron remnant
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GO_0034360 |
[A lipoprotein particle that is derived from a mature chylomicron particle by the removal of triglycerides from the chylomicron core by lipoprotein lipase and the subsequent loss of surface components. It characteristically contains apolipoprotein E (APOE) and is cleared from the blood by the liver.] |
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upstream stimulatory factor complex
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GO_1990378 |
[A protein complex capable of sequence-specific DNA binding RNA polymerase II transcription factor activity through binding to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3'). Found in a variety of viral and cellular promoters.] |
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lipid transport across blood-brain barrier
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GO_1990379 |
[The directed movement of lipid molecules passing through the blood-brain barrier.] |
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transport across blood-brain barrier
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GO_0150104 |
[The directed movement of substances (e.g. macromolecules, small molecules, ions) through the blood-brain barrier.] |