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regulation of heart rate by cardiac conduction
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GO_0086091 |
[A cardiac conduction process that modulates the frequency or rate of heart contraction.] |
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voltage-gated potassium channel activity involved in SA node cell action potential repolarization
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GO_0086090 |
[Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of an SA node cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.] |
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regulation of the force of heart contraction by cardiac conduction
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GO_0086092 |
[A cardiac conduction process that modulates the extent of heart contraction, changing the force with which blood is propelled.] |
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obsolete positive regulation of IKACh channel activity by G protein-coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate
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GO_0086095 |
[OBSOLETE. A G protein-coupled acetylcholine receptor signaling pathway that contributes to a decrease in frequency or rate of heart contraction through activation of the IKACh potassium channel. Binding of acetylcholine to a G protein-coupled acetylcholine receptor (muscarinic receptor) on the surface of the signal-receiving cell results in liberation of the G-beta/gamma complex from the alpha subunit. The G-beta/gamma complex binds directly to the inward-rectifying potassium channel IKACh. Once the ion channel is activated, potassium ions (K+) flow out of the cell and cause it to hyperpolarize. In its hyperpolarized state, action potentials cannot be fired as quickly as possible, which slows the heart rate.] |
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obsolete positive regulation of ryanodine-sensitive calcium-release channel activity by adrenergic receptor signaling pathway involved in positive regulation of cardiac muscle contraction
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GO_0086094 |
[OBSOLETE. An adrenergic receptor signaling pathway that contributes to an increase in frequency or rate of cardiac muscle contraction through phosphorylation and enhancement of the ryanodine receptor, a calcium-activated calcium-release channel found in the membrane of the sarcoplasmic reticulum. An adrenergic receptor-activated adenylate cyclase generates cAMP. cAMP then activates the cAMP-dependent protein kinase A (PKA), which phosphorylates the ryanodine receptor (RyR). PKA-phosphorylation of RyR enhances channel activity by sensitizing the channel to cytosolic calcium. Cytosolic calcium stimulates contractile proteins to promote muscle contraction.] |
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phospholipase C-activating angiotensin-activated signaling pathway
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GO_0086097 |
[A phospholipase C-activating G protein-coupled receptor signaling pathway initiated by angiotensin binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.] |
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obsolete adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process
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GO_0086096 |
[OBSOLETE. An adenylate cyclase-inhibiting adrenergic receptor signaling pathway which contributes to a circulatory system process carried out by the heart.] |
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phospholipase C-activating angiotensin-activated signaling pathway involved in heart process
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GO_0086099 |
[An angiotensin-mediated signaling pathway that contributes to a circulatory system process carried out by the heart, where the activated receptor transmits the signal via Gq-mediated activation of phospholipase C (PLC). PLC hydrolyses phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers inositol-1,4,5,-triphosphate (IP3) and diacylglycerol (DAG). DAG activates protein kinase C (PKC), whilst IP3 binds intracellular receptors to induce the release of Ca2+ from intracellular stores.] |
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angiotensin-activated signaling pathway involved in heart process
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GO_0086098 |
[An angiotensin receptor signaling pathway which contributes to a circulatory system process carried out by the heart.] |
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protein binding involved in heterotypic cell-cell adhesion
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GO_0086080 |
[Binding to a protein or protein complex contributing to the adhesion of two different types of cells.] |
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cell adhesive protein binding involved in AV node cell-bundle of His cell communication
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GO_0086082 |
[Binding to a protein or protein complex that results in the connection of an AV node cell with a bundle of His cell and contributes to the communication between the two cells.] |
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cell adhesive protein binding involved in atrial cardiac muscle cell-AV node cell communication
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GO_0086081 |
[Binding to a protein or protein complex that results in the connection of an atrial cardiomyocyte with an AV node cell and contributes to the communication between the two cells.] |
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cell adhesive protein binding involved in Purkinje myocyte-ventricular cardiac muscle cell communication
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GO_0086084 |
[Binding to a protein or protein complex that results in the connection of a Purkinje myocyte with an ventricular cardiac muscle cell and contributes to the communication between the two cells.] |
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cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication
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GO_0086083 |
[Binding to a protein or protein complex that results in the connection of a bundle of His cell with a Purkinje myocyte and contributes to the communication between the two cells.] |
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voltage-gated potassium channel activity involved in AV node cell action potential repolarization
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GO_0086086 |
[Catalysis of the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of an AV node cardiac muscle cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.] |
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cell adhesive protein binding involved in SA cardiac muscle cell-atrial cardiac muscle cell communication
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GO_0086085 |
[Binding to a protein or protein complex that results in the connection of an SA cardiomyocyte with an atrial cardiomyocyte and contributes to the communication between the two cells.] |
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voltage-gated potassium channel activity involved in Purkinje myocyte action potential repolarization
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GO_0086088 |
[Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a Purkinje myocyte contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.] |
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voltage-gated potassium channel activity involved in bundle of His cell action potential repolarization
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GO_0086087 |
[Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a bundle of His cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.] |
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voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization
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GO_0086089 |
[Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of an atrial cardiomyocyte contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.] |
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GO_0003728
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GO_0003728 |
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