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mediator complex assembly
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GO_0036034 |
[The aggregation, arrangement and bonding together of a set of components to form a mediator complex. The mediator complex is a protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins.] |
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mediator complex binding
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GO_0036033 |
[Binding to a mediator complex. The mediator complex is a protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins.] |
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regulation of action potential firing threshold
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GO_0099611 |
[Any process that regulates the potential at which an axon potential is triggered.] |
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obsolete recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex
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GO_0036031 |
[OBSOLETE. The process in which the guanylyltransferase enzyme responsible for adding a 7-methylguanosine cap on pre-mRNA becomes associated with the RNA polymerase II holoenzyme complex and the 5' end of a transcript.] |
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action potential initiation
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GO_0099610 |
[The initiating cycle of an action potential. In vertebrate neurons this typically occurs at an axon hillock. Not all initiated axon potentials propagate.] |
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protein localization to cell wall
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GO_0099613 |
[The process of directing proteins towards the cell-wall.] |
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obsolete bacterial cell surface binding
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GO_0051635 |
[OBSOLETE. Binding to a component on the surface of a bacterial cell.] |
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inhibition of acetylcholine uptake
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GO_0051634 |
[Any process that prevents the activation of the directed movement of acetylcholine into a cell.] |
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negative regulation of acetylcholine uptake
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GO_0051632 |
[Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of acetylcholine into a cell.] |
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GO_0075601
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GO_0075601 |
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(D)-2-hydroxyglutarate-pyruvate transhydrogenase activity
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GO_0099615 |
[Catalysis of the reaction: (R)-2-hydroxyglutarate + pyruvate = alpha-ketoglutarate + D-lactate, with FAD functioning as an intermediate hydrogen acceptor.] |
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obsolete Gram-positive bacterial cell surface binding
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GO_0051637 |
[OBSOLETE. Binding to a component on the surface of a Gram-positive bacterium.] |
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obsolete Gram-negative bacterial cell surface binding
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GO_0051636 |
[OBSOLETE. Binding to a component on the surface of a Gram-negative bacterial cell.] |
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matrix side of mitochondrial inner membrane
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GO_0099617 |
[The side (leaflet) of the mitochondrial inner membrane that faces the matrix.] |
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regulation of acetylcholine uptake
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GO_0051631 |
[Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter acetylcholine into a cell.] |
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extrinsic component of matrix side of mitochondrial inner membrane
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GO_0099616 |
[The component of the matrix side of the mitochondrial inner membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.] |
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acetylcholine uptake
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GO_0051630 |
[The directed movement of acetylcholine into a cell, typically presynaptic neurons or glial cells. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.] |
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UDP-4-amino-4-deoxy-L-arabinose formyltransferase activity
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GO_0099619 |
[Catalysis of the reaction: 10-formyltetrahydrofolate + UDP-4-amino-4-deoxy-beta-L-arabinopyranose = 5,6,7,8-tetrahydrofolate + UDP-4-deoxy-4-formamido-beta-L-arabinopyranose.] |
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positive regulation of acetylcholine uptake
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GO_0051633 |
[Any process that activates or increases the frequency, rate or extent of the directed movement of acetylcholine into a cell.] |
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UDP-glucuronic acid dehydrogenase activity
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GO_0099618 |
[Catalysis of the reaction: UDP-glucuronate + NAD+ = UDP-beta-L-threo-pentapyranos-4-ulose + CO2 + NADH + H+.] |