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NMDA selective glutamate receptor complex
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GO_0017146 |
[An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. NMDA receptors are composed of assemblies of NR1 subunits (Figure 3) and NR2 subunits, which can be one of four separate gene products (NR2A-D). Expression of both subunits are required to form functional channels. The glutamate binding domain is formed at the junction of NR1 and NR2 subunits. NMDA receptors are permeable to calcium ions as well as being permeable to other ions. Thus NMDA receptor activation leads to a calcium influx into the post-synaptic cells, a signal thought to be crucial for the induction of NMDA-receptor dependent LTP and LTD.] |
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ionotropic glutamate receptor complex
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GO_0008328 |
[A multimeric assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand-gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex.] |
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GO_0017144
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GO_0017144 |
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obsolete toxin susceptibility/resistance
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GO_0017142 |
[OBSOLETE. (Was not defined before being made obsolete).] |
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obsolete antibiotic susceptibility/resistance
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GO_0017141 |
[OBSOLETE. (Was not defined before being made obsolete).] |
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GO_0017140
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GO_0017140 |
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tRNA dihydrouridine synthase activity
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GO_0017150 |
[Catalysis of the reaction: a 5,6-dihydrouridine in tRNA + NAD(P)+ = a uridine in tRNA + H+ + NAD(P)H.] |
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RNA dihydrouridine synthase activity
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GO_0106413 |
[Catalysis of the reaction: RNA-uracil + NAD(P)+ = RNA-dihydrouridine + NAD(P)H + H+.] |
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NHE3/E3KARP/ACTN4 complex
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GO_0032766 |
[A heterotrimeric protein complex formed by the association of NHE3, E3KARP and alpha-actinin upon an increase in calcium ion concentration; found in clusters localized on plasma membrane and in intracellular compartments.] |
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positive regulation of mast cell cytokine production
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GO_0032765 |
[Any process that activates or increases the frequency, rate, or extent of mast cell cytokine production.] |
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copper-dependent protein binding
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GO_0032767 |
[Binding to a protein or protein complex, in the presence of copper.] |
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lead ion binding
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GO_0032791 |
[Binding to lead (Pb) ions.] |
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ribosome disassembly
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GO_0032790 |
[The disaggregation of a ribosome into its constituent components; includes the dissociation of ribosomal subunits.] |
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positive regulation of CREB transcription factor activity
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GO_0032793 |
[Any process that activates or increases the frequency, rate or extent of activity of the transcription factor CREB.] |
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neutrophil activation
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GO_0042119 |
[The change in morphology and behavior of a neutrophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.] |
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negative regulation of CREB transcription factor activity
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GO_0032792 |
[Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor CREB.] |
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negative regulation of DNA-binding transcription factor activity
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GO_0043433 |
[Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.] |
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endothelial cell activation
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GO_0042118 |
[The change in morphology and behavior of an endothelial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.] |
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heterotrimeric G-protein binding
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GO_0032795 |
[Binding to a heterotrimeric G-protein.] |
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monocyte activation
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GO_0042117 |
[The change in morphology and behavior of a monocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.] |