|
PAC-14028
|
DB12428 |
[PAC-14028 has been used in trials studying the treatment of Skin Pruritus, Papulopustular Rosacea, and Erythematotelangiectatic Rosacea.] |
|
Tetramethrin
|
DB13752 |
|
|
Somavaratan
|
DB12421 |
[Somavaratan has been used in trials studying the treatment of Growth Disorders and Adult Growth Hormone Deficiency.] |
|
Sulforaphane
|
DB12422 |
[Sulforaphane is under investigation for the treatment of Autism Spectrum Disorder. It is a naturally occurring isothiocyanate found in high concentration in a variety of broccoli.] |
|
Cetiedil
|
DB13753 |
|
|
Mephenoxalone
|
DB13754 |
|
|
Fozivudine Tidoxil
|
DB12423 |
[Fozivudine Tidoxil has been used in trials studying the treatment of HIV Infections.] |
|
Iocarmic acid
|
DB13755 |
|
|
MK-3207
|
DB12424 |
[Mk3207 has been used in trials studying the treatment of Migraine and Migraine Disorders.] |
|
Obidoxime
|
DB13750 |
|
|
Diazepinomicin
|
DB12420 |
[Diazepinomicin has been used in trials studying the treatment of Glioblastoma Multiforme. It is a proprietary first-in-class small molecule with the potential to treat multiple solid tumours like the well known chemotherapeutics, doxorubicin and mitomycin C. Diazepinomicin is a natural product derived from a non-pathogenic micro-organism. Discovered using Thallion’s DECIPHER technology, diazepinomicin has completed preclinical studies conducted by the National Cancer Institute and Thallion to establish safety and efficacy in animal and in vitro models.] |
|
Glycyrrhizic acid
|
DB13751 |
[Glycyrrhizic acid is extracted from the root of the licorice plant; _Glycyrrhiza glabra_.[F79] It is a triterpene glycoside with glycyrrhetinic acid that possesses a wide range of pharmacological and biological activities. When extracted from the plant, it can be obtained in the form of ammonium glycyrrhizin and mono-ammonium glycyrrhizin.[T204] Glycyrrhizic acid has been developed in Japan and China as a hepatoprotective drug in cases of chronic hepatitis.[A33062] From January 2014, glycyrrhizic acid as part of the licorice extract was approved by the FDA as an existing food sweetener.[F80] It was approved by Health Canada to be used in over-the-counter products but all the products are currently on the status canceled post marketed.[L1113]] |
|
8-Aminotheophylline
|
DB01778 |
|
|
Loracarbef
|
DB00447 |
[Loracarbef is a carbacephem antibiotic sometimes grouped together with the second-generation cephalosporin antibiotics. It is marketed under the trade name Lorabid.] |
|
Chloramphenicol
|
DB00446 |
[An antibiotic first isolated from cultures of _Streptomyces venequelae_ in 1947 but now produced synthetically. It has a relatively simple structure and was the first broad-spectrum antibiotic to be discovered. It acts by interfering with bacterial protein synthesis and is mainly bacteriostatic. (From Martindale, The Extra Pharmacopoeia, 29th ed, p106)] |
|
CoA-S-trimethylene-acetyl-tryptamine
|
DB01777 |
|
|
Dipivefrin
|
DB00449 |
[Dipivefrin is a prodrug of adrenaline, which is used to treat glaucoma. It is available as ophthalmic solution (eye drops).] |
|
Glycerol-2-Phosphate
|
DB01779 |
|
|
Lansoprazole
|
DB00448 |
[Lansoprazole marketed under the brand Prevacid, is a proton pump inhibitor (PPI) and is structurally classified as a substituted benzimidazole.[A177065] It reduces gastric acid secretion by targeting gastric H,K-ATPase pumps and is thus effective at promoting healing in ulcerative diseases, and treating gastroesophageal reflux disease (GERD) along with other pathologies caused by excessive acid secretion.[A177053]] |
|
Adenosine-5'-Monophosphate Glucopyranosyl-Monophosphate Ester
|
DB01774 |
[Serves as the glycosyl donor for formation of bacterial glycogen, amylose in green algae, and amylopectin in higher plants. [PubChem]] |
