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Piperaquine
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DB13941 |
[Piperaquine is an antimalarial agent first synthesized in the 1960's and used throughout China [A31550]. Its use declined in the 1980's as piperaquine resistant strains of *Plasmodium falciparum* appeared and artemisinin derivatives became available. It has come back into use in combination with the artemisinin derivative [DB11638] as part of the combination product Eurartesim [FDA Label]. Eurartesim was first authorized for market by the European Medicines Agency in October 2011.] |
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PF-477736
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DB12611 |
[PF-00477736 has been used in trials studying the treatment of Neoplasms.] |
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Inulin
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DB00638 |
[A starch found in the tubers and roots of many plants. Since it is hydrolyzable to fructose, it is classified as a fructosan. It has been used in physiologic investigation for determination of the rate of glomerular function.] |
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Trifluoroacetonyl coenzyme A
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DB01969 |
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Astemizole
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DB00637 |
[Astemizole is a long-acting, non-sedating second generation antihistamine used in the treatment of allergy symptoms. It was withdrawn from market by the manufacturer in 1999 due to the potential to cause arrhythmias at high doses, especially when when taken with CYP inhibitors or grapefruit juice.] |
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2-Thioethenamine
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DB01968 |
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Butoconazole
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DB00639 |
[Butoconazole is an imidazole antifungal used in gynecology.] |
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2'-Deoxyuridine 5'-alpha,beta-imido-triphosphate
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DB01965 |
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Sulfacetamide
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DB00634 |
[An anti-infective agent that is used topically to treat skin infections and orally for urinary tract infections.] |
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AL5424
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DB01964 |
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Dexmedetomidine
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DB00633 |
[An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.] |
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Clofibrate
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DB00636 |
[A fibric acid derivative used in the treatment of hyperlipoproteinemia type III and severe hypertriglyceridemia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p986)] |
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N-{3-[(7ar,12as,12bs)-7-Oxo-1,3,4,6,7,7a,12a,12b-Octahydroindolo[2,3-a]Quinolizin-12(2h)-Yl]Propyl}Propane-2-Sulfonamide
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DB01967 |
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Prednisone
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DB00635 |
[A synthetic anti-inflammatory glucocorticoid derived from [cortisone].[A187463] It is biologically inert and converted to [prednisolone] in the liver.[L10502]
Prednisone was granted FDA approval on 21 February 1955.[L10496]] |
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Di-Stearoyl-3-Sn-Phosphatidylethanolamine
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DB01966 |
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Alendronic acid
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DB00630 |
[Alendronic acid is a bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959]. It functions by preventing resorption of bone[FDA Label][A959].] |
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Cytidine 3'-monophosphate
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DB01961 |
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7-methyl-7,8-dihydroguanosine-5'-diphosphate
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DB01960 |
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Phenylethane Boronic Acid
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DB01963 |
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Docosanol
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DB00632 |
[Docosanol is a drug used for topical treatment for recurrent herpes simplex labialis episodes (episodes of cold sores or fever blisters). A saturated 22-carbon aliphatic alcohol, docosanol exhibits antiviral activity against many lipid enveloped viruses including herpes simplex virus (HSV). Docosanol inhibits fusion between the plasma membrane and the herpes simplex virus (HSV) envelope, thereby preventing viral entry into cells and subsequent viral replication.] |
