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Tideglusib
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NCIT_C97364 |
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Haploviricotina
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NCBITaxon_2497570 |
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brain
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UBERON_0000955 |
[The brain is the center of the nervous system in all vertebrate, and most invertebrate, animals. Some primitive animals such as jellyfish and starfish have a decentralized nervous system without a brain, while sponges lack any nervous system at all. In vertebrates, the brain is located in the head, protected by the skull and close to the primary sensory apparatus of vision, hearing, balance, taste, and smell[WP].] |
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G2/M transition of mitotic cell cycle
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GO_0000086 |
[The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex.] |
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Cathepsin
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NCIT_C16389 |
[Lysosomal proteinases or endopeptidases that function optimally at an acidic pH to catalyze the hydrolysis of peptidic bonds. Elevated cathepsin enzyme activity in either serum or extracellular matrix is often indicative of pathological conditions such as Alzheimer's disease, several types of cancer, arthritis, and osteoporosis.] |
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regulation of transcription involved in G1/S transition of mitotic cell cycle
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GO_0000083 |
[Any process that regulates transcription such that the target genes are involved in the transition between G1 and S phase of the mitotic cell cycle.] |
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regulation of plasminogen activation
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GO_0010755 |
[Any process that modulates the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin.] |
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G1/S transition of mitotic cell cycle
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GO_0000082 |
[The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated.] |
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SARS coronavirus GD01
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NCBITaxon_233044 |
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sarilumab
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DRON_00789755 |
[A recombinant, human immunoglobulin (IgG) monoclonal antibody targeting the interleukin 6 receptor (IL-6R), with potential anti-inflammatory activity. Upon intravenous administration of sarilumab, this agent targets and binds to both soluble IL-6 receptor (sIL-6R) and membrane-bound IL-6 receptor (mIL-6R). This inhibits the binding of the pro-inflammatory cytokine IL-6 to the IL-6 receptor (IL-6R), which results in the blockade of the IL-6/IL-6R-mediated signal transduction pathway. This may inhibit IL-6/IL-6R-mediated inflammation.] |
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DNA replication
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GO_0006260 |
[The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.] |
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blood coagulation
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GO_0007596 |
[The sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.] |
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Chinese Herbs
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NCIT_C2663 |
[Herbs used in Chinese Herbal Therapy for toxicity attenuation. (NCI)] |
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Respiratory distress
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HP_0002098 |
[Difficulty in breathing. The physical presentation of respiratory distress is generally referred to as labored breathing, while the sensation of respiratory distress is called shortness of breath or dyspnea.] |
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Dyspnea
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HP_0002094 |
[Difficult or labored breathing.] |
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Monoclonal Antibody
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NCIT_C20401 |
[An antibody produced by a clone or genetically homogenous fast-growing cells i.e., hybridoma. Hybridoma cells are cloned to establish cell lines producing a specific antibody that is chemically and immunologically homogeneous. They are widely used in cancer detection, diagnosis, and treatment.] |
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eye
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UBERON_0000970 |
[An organ that detects light.] |
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NKRF
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OGG_3000055922 |
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TNFSF10
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OGG_3000008743 |
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ssRNA viruses
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NCBITaxon_439488 |
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