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remdesivir
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CHEBI_145994 |
[A carboxylic ester resulting from the formal condensation of the carboxy group of N-[(S)-{[(2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(phenoxy)phosphoryl]-L-alanine with the hydroxy group of 2-ethylbutan-1-ol. A broad-spectrum antiviral prodrug with potent in vitro antiviral activity against a diverse panel of RNA viruses such as Ebola virus, MERS-CoV and SARS-CoV. It is currently in Phase III clinical trials for the treatment of Covid-19 in adults.] |
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thrombocytopenia
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SYMP_0000114 |
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head and neck symptom
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SYMP_0000597 |
[Symptoms that manifest in any of the part of head and neck] |
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quality
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BFO_0000019 |
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Abnormality of the genitourinary system
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HP_0000119 |
[The presence of any abnormality of the genitourinary system.] |
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Recurrent lower respiratory tract infections
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HP_0002783 |
[An increased susceptibility to lower respiratory tract infections as manifested by a history of recurrent lower respiratory tract infections.] |
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Recurrent respiratory infections
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HP_0002205 |
[An increased susceptibility to respiratory infections as manifested by a history of recurrent respiratory infections.] |
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modulation by virus of host NIK/NF-kappaB signaling
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GO_0061765 |
[Any process in which a virus effect a change in the frequency, rate or extent of NIK/NF-kappaB signaling in the host.] |
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conjunctivitis
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SYMP_0000128 |
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organ part
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UBERON_0000064 |
[A multicellular structure that is a part of an organ.] |
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complement activation
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GO_0006956 |
[Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.] |
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humoral immune response
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GO_0006959 |
[An immune response mediated through a body fluid.] |
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Riboviria
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NCBITaxon_2559587 |
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complement activation, classical pathway
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GO_0006958 |
[Any process involved in the activation of any of the steps of the classical pathway of the complement cascade which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes.] |
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heart inflammation
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MP_0001853 |
[local accumulation of fluid, plasma proteins, and leukocytes in the heart] |
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ficolin-1-rich granule membrane
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GO_0101003 |
[The lipid bilayer surrounding a ficolin-1-rich granule.] |
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ficolin-1-rich granule
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GO_0101002 |
[Highly exocytosable gelatinase-poor granules found in neutrophils and rich in ficolin-1. Ficolin-1 is released from neutrophil granules by stimulation with fMLP or PMA, and the majority becomes associated with the surface membrane of the cells and can be detected by flow cytometry.] |
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mRNA cis splicing, via spliceosome
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GO_0045292 |
[The joining together, after removal of an intervening sequence composed of one or more introns, of two segments of the same RNA molecule via spliceosomal catalysis to produce an mRNA composed only of exon sequences that all came from the same primary transcript.] |
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seizure
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SYMP_0000124 |
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Parenchymal consolidation
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HP_0032177 |
[Consolidation refers to an exudate or other product of disease that replaces alveolar air, rendering the lung solid (as in infective pneumonia).] |