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adenosine
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CHEBI_16335 |
[A ribonucleoside composed of a molecule of adenine attached to a ribofuranose moiety via a beta-N(9)-glycosidic bond.] |
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suppression by virus of host IRF3 activity
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GO_0039548 |
[Any process in which a virus stops, prevents, or reduces the activity of host IRF3 (interferon regulatory factor-3), a transcription factor in the RIG-I/MDA-5 signaling pathway. Viral infection triggers phosphorylation of cytoplasmic IRF3, which allows IRF3 to form a homodimer, migrate to the nucleus, and activate transcription of IFN-alpha and IFN-beta genes.] |
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host
|
IDO_0000531 |
[An organism bearing a host role.] |
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SARS coronavirus BJ202
|
NCBITaxon_321149 |
|
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positive regulation of establishment of protein localization
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GO_1904951 |
[Any process that activates or increases the frequency, rate or extent of establishment of protein localization.] |
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Ground-glass opacification on pulmonary HRCT
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HP_0025179 |
[A descriptive term that is applied to computer tomography imaging and that refers to a hazy area of increased attenuation in the lung with preserved bronchial and vascular markings.] |
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SARS coronavirus BJ162
|
NCBITaxon_321147 |
|
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late endosome
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GO_0005770 |
[A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.] |
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suppression by virus of host MAVS activity
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GO_0039545 |
[Any process in which a virus stops, prevents, or reduces the activity of MAVS (mitochondrial antiviral signaling protein), a signal transducer that lies downstream of the viral RNA receptors MDA-5 and RIG-I to coordinate host innate immune responses.] |
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gamma-glutamyltransferase
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COVID_0000107 |
|
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cyclosporin A
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CHEBI_4031 |
[A cyclic nonribosomal peptide of eleven amino acids; an immunosuppressant drug widely used in post-allogeneic organ transplant to reduce the activity of the patient's immune system, and therefore the risk of organ rejection. Also causes reversible inhibition of immunocompetent lymphocytes in the G0- and G1-phase of the cell cycle.] |
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IGHE
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OGG_3000003497 |
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FABP4
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OGG_3000002167 |
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chloramphenicol
|
CHEBI_17698 |
[An organochlorine compound that is dichloro-substituted acetamide containing a nitrobenzene ring, an amide bond and two alcohol functions.] |
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Centrilobular ground-glass opacification on pulmonary HRCT
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HP_0025180 |
[A hazy area of increased attenuation in centrilobular areas of the lung with preserved bronchial and vascular markings seen on a computer tomography scan. Centrilobular refers to a location that is central within secondary pulmonary lobules.] |
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Sepsis
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HP_0100806 |
[Systemic inflammatory response to infection.] |
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mycophenolic acid
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CHEBI_168396 |
[A member of the class of 2-benzofurans that is 2-benzofuran-1(3H)-one which is substituted at positions 4, 5, 6, and 7 by methyl, methoxy, (2E)-5-carboxy-3-methylpent-2-en-1-yl, and hydroxy groups, respectively. It is an antibiotic produced by Penicillium brevi-compactum, P. stoloniferum, P. echinulatum and related species. An immunosuppressant, it is widely used (partiularly as its sodium salt and as the 2-(morpholin-4-yl)ethyl ester prodrug, mycophenolate mofetil) to prevent tissue rejection following organ transplants and for the treatment of certain autoimmune diseases.] |
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apical dendrite
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GO_0097440 |
[A dendrite that emerges near the apical pole of a neuron. In bipolar neurons, apical dendrites are located on the opposite side of the soma from the axon.] |
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endoplasmic reticulum lumen
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GO_0005788 |
[The volume enclosed by the membranes of the endoplasmic reticulum.] |
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blood microparticle
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GO_0072562 |
[A phospholipid microvesicle that is derived from any of several cell types, such as platelets, blood cells, endothelial cells, or others, and contains membrane receptors as well as other proteins characteristic of the parental cell. Microparticles are heterogeneous in size, and are characterized as microvesicles free of nucleic acids.] |