All terms in COVID

Label Id Description
Leronlimab NCIT_C137824 [A humanized immunoglobulin (Ig) G4 monoclonal antibody against CC chemokine receptor 5 (CCR5; CD195), with potential activity as a human immunodeficiency virus (HIV) entry blocker and potential protective activity against graft-versus-host disease (GvHD). Upon administration, leronlimab targets and binds to CCR5 expressed on T-cells. This blocks HIV cell entry, which prevents HIV infection and/or reduces HIV viral load. In addition, blocking CCR5 by PRO 140 decreases CCR5-mediated signaling and the CCR5-induced migration of donor cells into tissues after an allogeneic hematopoietic cell transplantation (HCT). Blocking CCR5 may therefore prevent or reduce GvHD. CCR5, a co-receptor needed for HIV cell entry, plays a key role in immunomodulation. Expressed on monocytes, activated T-cells and dendritic cells (DCs), CCR5 can regulate chemotaxis. Lymphocyte trafficking via chemokine receptors, such as CCR5, and recruitment to target organs, plays a critical role in alloreactive responses.]
drug CHEBI_23888 [Any substance which when absorbed into a living organism may modify one or more of its functions. The term is generally accepted for a substance taken for a therapeutic purpose, but is also commonly used for abused substances.]
acquired metabolic disease DOID_0060158 [A disease of metabolism that has _material_basis_in enzyme deficiency or accumulation of enzymes or toxins which interfere with normal function due to an endocrine organ disease, organ malfunction, inadequate intake, dietary deficiency, or malabsorption.]
disease of metabolism DOID_0014667 [A disease that involving errors in metabolic processes of building or degradation of molecules.]
axon guidance GO_0007411 [The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.]
neuron projection guidance GO_0097485 [The process in which the migration of a neuron projection is directed to a specific target site in response to a combination of attractive and repulsive cues.]
positive regulation by virus of host cytokine production GO_0044832 [The process in which a virus increases the frequency, rate or extent of cytokine production in its host organism.]
modulation by virus of host cytokine production GO_0044831 [Any process in which a virus modulates the frequency, rate or extent of cytokine production in its host organism.]
nuclear matrix GO_0016363 [The dense fibrillar network lying on the inner side of the nuclear membrane.]
cellular_component GO_0005575 [A location, relative to cellular compartments and structures, occupied by a macromolecular machine when it carries out a molecular function. There are two ways in which the gene ontology describes locations of gene products: (1) relative to cellular structures (e.g., cytoplasmic side of plasma membrane) or compartments (e.g., mitochondrion), and (2) the stable macromolecular complexes of which they are parts (e.g., the ribosome).]
kidney epithelium development GO_0072073 [The process whose specific outcome is the progression of an epithelium in the kidney over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.]
bodily process OGMS_0000060 [A process in which at least one bodily component of an organsim participates.]
cell cycle G2/M phase transition GO_0044839 [The cell cycle process by which a cell in G2 phase commits to M phase.]
cellular process GO_0009987 [Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.]
disinfectant CHEBI_48219 [An antimicrobial agent that is applied to non-living objects to destroy harmful microorganisms or to inhibit their activity.]
chemical entity CHEBI_24431 [A chemical entity is a physical entity of interest in chemistry including molecular entities, parts thereof, and chemical substances.]
Baloxavir marboxil DRON_00837844 [An orally bioavailable prodrug and influenza cap-dependent endonuclease (CEN) inhibitor, with antiviral activity. Upon administration of baloxavir marboxil, the agent is converted by hydrolysis to its active metabolite baloxavir. Baloxavir targets, binds to and inhibits the CEN activity of the influenza polymerase acidic (PA) protein, an influenza virus-specific enzyme in the viral RNA polymerase complex required for the initiation of influenza gene transcription.]
cardiovascular measurement CMO_0000001
clinical measurement CMO_0000000
measurement datum IAO_0000109 [A measurement datum is an information content entity that is a recording of the output of a measurement such as produced by a device.]